Skip to main content

Table 2 Associations between Project Lazarus implementation and opioid analgesic prescribing, by strategy, North Carolina, 2009–2014

From: Associations between implementation of Project Lazarus and opioid analgesic dispensing and buprenorphine utilization in North Carolina, 2009–2014

     Univariate Modelsa Multivariable Adjusted Modelb
Strategy Implementation Level County-months Rx OAs dispensed IRR 95% CI CLR IRR 95% CI CLR
Diversion Control None 4971 23,512,894 1 (ref.)    1 (ref.)   
Any 2229 17,848,868 1.15 1.12, 1.17 1.044 1.06 1.03, 1.09 1.056
Naloxone Policies None 6216 34,103,605 1 (ref.)    1 (ref.)   
Any 984 7,258,157 1.08 1.06, 1.11 1.038 0.97 0.95, 0.99 1.048
Community Education None 5969 30,353,079 1 (ref.)    1 (ref.)   
Any 1231 11,008,683 1.11 1.09, 1.13 1.042 1.00 0.97, 1.03 1.058
Provider Education None 4962 25,608,213 1 (ref.)    1 (ref.)   
Any 2238 15,753,549 1.13 1.10, 1.15 1.042 1.00 0.97, 1.03 1.060
Support for Patients with Pain None 6684 34,023,002 1 (ref.)    1 (ref.)   
Any 516 7,338,760 1.08 1.06, 1.10 1.029 0.96 0.93, 1.00 1.069
Hospital ED Policy None 5485 29,009,970 1 (ref.)    1 (ref.)   
Any 1715 12,351,792 1.11 1.08, 1.13 1.047 0.99 0.96, 1.01 1.055
Addiction Treatment None 1559 13,442,436 1 (ref.)    1 (ref.)   
Any 5641 27,919,326 1.16 1.11, 1.20 1.085 1.04 0.99, 1.08 1.090
  1. IRR incidence rate ratio, CI confidence interval, CLR confidence limit ratio, ED Emergency Department
  2. Results from Poisson GEE with county-month population offset
  3. aUnivariate unadjusted models for each strategy
  4. bAdjusted multivariable model adjusts for the other six strategies, county health status, year and season