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Table 4 Four-way decomposition of the total effect of marijuana use on fatal 2-vehicle crash initiation in the presence of alcohol

From: Direct and indirect effects of marijuana use on the risk of fatal 2-vehicle crash initiation

Component Log (Odds Ratio) 95% Confidence Interval Effect Proportion P value
Total Effect 0.499 0.31, 0.66 1.00 < 0.001
Controlled Direct Effect 0.257 0.16, 0.36 0.515 < 0.001
Reference Interaction 0.086 −0.04, 0.21 0.173 0.181
Mediated Interaction 0.039 −0.02,0.10 0.078 0.205
Pure Indirect Effect 0.117 0.05, 0.18 0.234 0.001
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