Cohort study of medical cannabis authorization and motor vehicle crash-related healthcare visits in 2014–2017 in Ontario, Canada

Table 3 Interrupted time series analysis of healthcare utilization due to motor vehicle crash six months before and six months after authorization of medical cannabis compared to those unauthorized (n = 27,657)

Outcome	Authorized Medical Cannabis				Unauthorized Controls				Difference
	Immediate Level Change*		Temporal Trend change**		Immediate Level Change*		Temporal Trend Change**		Immediate Level Change*		Temporal Trend Change**
	Events/ 10,000 patients	p-value	Events/ 10,000 patients	p-value	Events/10,000 patients	p-value	Events/ 10,000 patients	p-value	Events/ 10,000 patients	p-value	Events/ 10,000 patients	P-value
Motor-vehicle related hospitalization or ED visit	−3.15	0.3988	0.50	0.61	−2.38	0.2879	−0.31	0.64	−2.42	0.0138	0.89	0.0019
Absolute Effect Motor-vehicle related hospitalization or ED visit									Events/10,000 patients 2.92		95% Confidence Intervals 0.64–5.19
Motor-vehicle related hospitalization	−1.97	0.0365	0.22	0.2753	−0.91	0.0749	−0.068	0.5782	−1.10	0.7322	−0.0081	0.9898
Absolute Effect Motor-vehicle related hospitalization									Events/10,000 patients − 1.15		95% Confidence Intervals (− 14.63–12.33)
Motor-vehicle related ED	− 1.91	0.5108	0.64	0.4184	−1.42	0.4661	−0.18	0.7384	−0.90	0.2907	0.80	0.0001
Absolute Effect Motor-vehicle related ED visit									Events/10,000 patients 3.92		95% Confidence Intervals (2.65–5.19)

*change in the month following the authorization of cannabis or the index date
**change in slope in the six months following the authorization of cannabis or the index date
ED Emergency department

ISSN: 2197-1714